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☞ 01/06/2026
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Art & Science

 

Resonating Intuitions: where musical structure meets scientific creativity


Following the enthusiastic participation recorded during Nanosea 2024 in Marseille, we return to explore the fascinating intersection between artistic creativity and scientific rigor.

 


This year, we have chosen to frame this dialogue in a deeply intimate and biological key. Indeed, the history of science teaches us that the link between musical structure and the freedom of scientific intuition is not a coincidence, but a fundamental cognitive synergy. In the Middle Ages, the Benedictine nun Hildegard of Bingen combined the writing of visionary treatises on empirical medicine with the composition of sacred music. Centuries later, Albert Einstein confessed that he conceived his most revolutionary thoughts in physics through the strings of his violin, while Max Planck was a talented pianist. In modern times, Brian May combined his role as the guitarist of Queen with that of an astrophysicist, while Fabiola Gianotti earned a diploma in piano from the Milan Conservatory before dedicating herself to subnuclear physics.

 

This leads us to wonder: what happens, then, at a neuroscientific level when these two disciplines meet? How does musical training enhance brain plasticity, problem-solving, and the ability to visualize complex models in scientific research?

 

Two key moments will make this edition special. First, the speech by Prof. Filippo Caraci (University of Catania and Oasi Research Institute-IRCCS, Troina, Italy), who not only will show us how music activates brain networks related to attention, imagination, emotions, and problem-solving, but will also demonstrate that these cognitive processes are the same ones used in scientific research to design experiments and formulate new hypotheses. Subsequently, the piano concert by Maestro Alberto Giambello explores the transition from 18th-century harpsichord-fortepiano style to Romantic piano playing, performing pieces by Haydn, Clementi, Mozart, and Beethoven. The first part highlights the post-harpsichord elements in Haydn and Clementi, while the second focuses on Mozart's expressive maturity and Beethoven's revolutionary cantabile style.

 

Through these contributions, this symposium will seek to decode this mysterious and powerful bond. We invite you to listen to these sessions not only as scientists but as explorers of human creativity, to discover how the harmony of music can ignite the spark of the next great scientific discovery.

 


Music and Scientific Creativity: is there a link?

Filippo Caraci


Department of Drug and Health Sciences University of Catania, Italy; Oasi Research Institute-IRCCS, Unit of Translational Neuropharmacology and Translational Neurosciences, Troina, Italy

 

Music can enhance scientific creativity, and functional MRI (fMRI) helps reveal the brain mechanisms that link musical activity with creative thinking. Making or listening to music strongly engages networks involved in attention, imagination, emotion, and flexible problem solving processes that are also central to scientific creativity. Listening to and especially creating music recruit broad brain networks, including auditory regions, the prefrontal cortex (planning and innovation), and the default mode network (mind wandering and idea generation). Different studies of composers and improvisers show that music creation activates areas linked to working memory, motor planning, and emotional regulation, which are also key for designing experiments and generating novel hypotheses in science.

 

In the present lecture we will discuss how music musical creativity relies on distributed, multimodal networks rather than one single “creativity center and how musical training and improvisation strengthen connectivity between sensory, motor, and higher order cognitive networks.
Music increases aesthetic sensitivity and divergent thinking scores, which fMRI studies connect to shifts in default mode and attention network responses. This can explay why musicians often show enhanced fluid intelligence, pattern recognition, and cognitive flexibility—all traits that support scientific innovation. Music recruits the Salience Network to toggle the connection between the DMN (imagination) and the Executive Network (control), which is the exact mechanism for "Scientific Creativity".

 



The Effect of Sonata K448 on brain networks



Finally, Music can exert a therapeutic action resetting the networks exposed to chronic stress and normalizing default mode network (DMN) iperactivity in depressed patients, where the DMN often shows hyperconnectivity within itself and altered connectivity with attention and control networks, a linkage with excessive self referential thinking and rumination, which are core features of depressive blocks. Interestingly, music based interventions can shift DMN coupling and connectivity in directions that may help reduce rumination and depressive symptoms, especially when combined with active or improvisational components.

 

 

 

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